Although side effects are usually very mild, the flu shot can cause pain, redness, or swelling where the shot was given. A few people may also experience body aches or a low fever. Hives on the skin. The appearance of hives can signal an allergic reaction to the flu shot.
In rare cases, the flu shot can cause a severe allergic reaction. When this happens, it usually occurs within minutes or hours after the shot is given. The following are signs that require emergency treatment:
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