Johns Hopkins Researchers Create New Mouse Model Of Autism

Monday, Aug. 1st 2011 6:40 AM

In an effort to unravel the tangled biology of autism, Johns Hopkins scientists have created a mouse model that mimics a human mutation of a gene known to be associated with autism spectrum disorders. Experiments with the engineered mouse reveal a molecular mechanism by which mutations of the gene named Shank3 affect the brain and behavior to evoke an autism-like disorder in mice.

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